Energy Production
Copper helps enzymes involved in normal cellular energy production do their work.
Concentrated care for dry-feeling skin
Massage Copper1 MAX Z™ into clean, intact skin wherever extra conditioning is desired—from hands and elbows to knees and feet.
4.9 from 35 Google reviews for Jefro's Botanicals
Why copper matters
Copper is an essential trace mineral. Your body only needs it in small amounts, but copper-dependent enzymes participate in fundamental biological processes throughout the body.
Copper helps enzymes involved in normal cellular energy production do their work.
Copper is required for normal iron metabolism. Copper-containing proteins such as ceruloplasmin help the body process and transport iron so it can be used appropriately.
Copper-dependent enzymes participate in the formation and maintenance of connective tissues that help give structure to the body.
Copper contributes to normal nervous-system processes and the activity of enzymes involved in neurotransmitter biology.
Adequate copper nutrition helps support normal immune-system function.
Copper is part of enzymes, including copper-containing superoxide dismutases, that participate in the body’s normal defense against oxidative damage.
What makes Bio-Cu1® different?
Bio-Cu1® brings copper education and copper-focused products together without pretending that every copper product does the same thing.
Topical · external use
A concentrated, water-free botanical balm containing Copper1 (Cunermuspir).
It is designed for:
Copper1 MAX Z™ is not a dietary supplement and should not be presented as a way to increase dietary copper intake or produce systemic nutritional effects.
Explore Copper1 MAX Z™Oral · dietary supplement
MitoActivator EX is an oral MitoSynergy dietary supplement containing BioCopper1®.
According to its Supplement Facts label, each capsule provides:
Unlike the topical balm, MitoActivator EX is intended to contribute copper to the diet as an oral dietary supplement.
Use dietary supplements according to their label and discuss supplementation with a qualified healthcare professional when appropriate.
Explore MitoActivator EXWhy Copper1?
“Copper1” refers to copper in the +1 oxidation state, Cu⁺, also called copper(I).
Copper chemistry is complex. Within biology, copper can participate in oxidation-reduction chemistry involving different oxidation states, and copper-containing enzymes use that chemistry to perform important functions.
Bio-Cu1® focuses on Copper1 because we believe consumers should understand that “copper” is not one simple material or one single formulation.
Know the form. Understand what kind of copper a product contains.
Know the route. A topical balm and an oral dietary supplement are not interchangeable.
Know the amount. We clearly disclose Copper1 loading in Copper1 MAX Z™ and the labeled dietary copper amount in MitoActivator EX.
Know the formulation. Copper1 MAX Z™ uses an oil-rich, water-free topical system designed around its Copper1 ingredient.
Know the limits of the evidence. Established nutritional science about copper should not be turned into unsupported claims that a particular Bio-Cu1® product prevents, treats, or cures disease.
Education before exaggeration.
Copper is an essential nutrient. That established fact is different from claiming that one particular copper product produces a medical outcome.
Bio-Cu1® is committed to keeping those two conversations separate.
Know your copper before you choose your copper.™Read the NIH Office of Dietary Supplements Copper Fact SheetQuick answers
The flagship
Shea butter, mango butter, beeswax, and botanical oils create a protective-feeling layer for dry, rough-feeling areas.
Every 2 oz tin contains 132 mg of Copper1 (Cunermuspir), held in a water-free, oil-rich formula designed around copper(I) stability.
The concentrated texture is easy to warm between your fingertips and massage into intact skin as part of a morning or evening routine.
“Wonderful soft, silky texture.”
Jazmine U. · Google review
“This stuff is the truth!”
Cuenique S. · Google review
“10 out of 10!”
Britt K. · Google review
The Bio-Cu1® difference
Copper1 MAX Z™ was built around a specific formulation priority: keep the copper(I) ingredient suspended in an oil-based system while creating a premium balm people can incorporate into everyday care.
Your daily ritual
Warm a small amount between clean fingertips.
Apply to clean, intact skin where extra conditioning is desired.
Massage gently until the balm settles into the skin.
Repeat as part of a mindful daily wellness routine.
Choose your size
Same focused formula in four available sizes.
International shipping: a separate $45.00 USD payment is required once per order outside the United States and U.S. Virgin Islands. See the required international shipping steps. Compare sizes here, then choose 0.5 oz, 1 oz, 2 oz, or 5 oz on the secure Square checkout page. Questions? Call 1-855-369-3366.

MitoSynergy dietary supplement
$38.95 60 capsules
BioCopper1® extra strength copper capsules from MitoSynergy. The bottle’s Supplement Facts list 0.5 mg copper and 1.9 mg niacin per capsule. Browse the front, facts, and side label photos for full packaging details.
Buy MitoActivator EX · $38.95International shipping: a separate $45.00 USD payment is required once per order outside the United States and U.S. Virgin Islands. See the required international shipping steps. Complete payment on the secure checkout page. U.S. shipping and applicable taxes are shown there.
Bio-Cu1® bundle
Shop The Copper Trio for $89.95 through secure BioCu1 Square checkout. A separate $45.00 USD international shipping payment is required once per order outside the United States and U.S. Virgin Islands. See the required international shipping steps. U.S. shipping and applicable taxes are shown at checkout.

Continue the education
Discover copper’s hidden history—from ancient civilizations to modern wellness. This accessible guide examines long-standing myths and the science behind copper’s role in human health.
Shipping outside the United States and U.S. Virgin Islands? A separate $45.00 USD international shipping payment is required, once per order.
Orders outside the U.S. and U.S. Virgin Islands
$45.00 USD per order is required for destinations outside the United States and U.S. Virgin Islands, regardless of the number of items.
Step 1: Purchase your products and enter the delivery address on the product checkout. Step 2: Return here and pay the $45.00 shipping fee once for that order, using the same name and email.
International orders are released for shipment after the separate shipping payment is received and matched to the product order. The shipping payment does not include products or collect your delivery address. If checkout rejects your address, call 1-855-369-3366 before paying the shipping fee.
Good to know
Copper1 MAX Z™ is a topical wellness balm made with botanical oils, rich plant butters, and Copper1 (Cunermuspir), a copper(I) ingredient. Choose 0.5 oz, 1 oz, 2 oz, or 5 oz for external skin-conditioning and daily wellness use.
Choose 0.5 oz to try the balm with the lowest upfront cost, 1 oz for travel, 2 oz for regular use, or 5 oz for the lowest cost per ounce. Every size uses the same Copper1 MAX Z™ formula.
Apply a small amount to clean, intact skin and massage gently. Start with a patch test. Avoid eyes, mucous membranes, and broken skin, and stop use if irritation occurs.
The copper(I) ingredient is suspended in an oil-rich base as part of the product’s stability-focused formulation. The balm format also provides an emollient layer that helps soften and condition the skin.
The formula includes beeswax, shea butter, mango butter, MCT oil, black seed oil, hemp seed oil, oregano essential oil, peppermint essential oil, a brown sugar fragrance and essential-oil blend, vitamin E, and Copper1 (Cunermuspir).
Use a small amount on clean, intact skin—especially dry-feeling areas such as hands, elbows, knees, or anywhere you enjoy a concentrated massage balm. Patch test first and avoid eyes, mucous membranes, and broken skin.
No. Bio-Cu1.com is the dedicated home of Bio-Cu1® and Copper1 MAX Z™ wellness products. CBD products are kept separate and are not offered on this site.
All products use secure BioCu1 Square checkout. Choose your Copper1 MAX Z size or book format on the Square page; MitoActivator EX has its own checkout page. Free standard U.S. shipping is included for the balm. For destinations outside the United States and U.S. Virgin Islands, a separate $45.00 USD international shipping payment is required once per order, regardless of the number of items. Purchase your products first, then use the International shipping section on this page with the same name and email. International orders are released for shipment after the separate shipping payment is received and matched to the product order. U.S. shipping for other products and applicable taxes are shown at checkout.
The Truth About Copper! is Jarrett K. St. Amand’s guide to copper’s history and its role in human health and wellness. The book is sold separately from Copper1 MAX Z™, with U.S. shipping calculated at checkout and international shipping at $45.00 USD per order.
MitoActivator EX is a MitoSynergy BioCopper1 dietary supplement sold in a 60-capsule bottle. According to the bottle label, each capsule provides 0.5 mg copper and 1.9 mg niacin. International shipping is $45.00 USD per order. U.S. shipping and applicable taxes are shown at checkout.
Bioactive wellness, redefined
Shop 0.5 oz, 1 oz, 2 oz, or 5 oz with free U.S. shipping. A separate $45.00 USD payment is required for orders shipped outside the United States and U.S. Virgin Islands.
Choose your Copper1 MAX Z™